They affect what we eat and the way we feel. World’s Most Powerful Women Their decisions impact everything from the polls to our purses. Get inspired by our list of alpha-female leaders and moguls who make the world go ‘round. Michelle Obama The first lady has the ear and the confidence of the commander in chief. She has made headlines with her nationwide anti-obesity program. (Some of the press has been negative.) Also on her agenda: supporting the arts and helping troops. Hillary Clinton Secretary of State Clinton took her oath of office in January 2009. The former first lady and senator now heads up global initiatives, discusses weighty issues at home and tackles grave dilemmas abroad. Angela Merkel Chancellor of Germany Merkel — now serving her second term — holds a historically significant title. In her post, she has her finger on the pulse of this major power. Oprah Winfrey The media mogul has dominated the talk show scene (for how long?) and tapped into print media, r...